導(dǎo)師簡介
姓名:孫李斌 性別:男 政治面貌:群眾
學(xué)歷:研究生 學(xué)位:醫(yī)學(xué)博士 職稱: 副主任醫(yī)師
博、碩導(dǎo)師: 碩士生導(dǎo)師 本崗位工作年數(shù):8年
研究方向:
尿路上皮癌的腹腔鏡微創(chuàng)治療及多發(fā)復(fù)發(fā)膀胱癌的個(gè)體化治療
榮譽(yù)稱號:
山西省“三晉英才”支持計(jì)劃首批青年優(yōu)秀人才
國家臨床重點(diǎn)??乒歉扇瞬?/span>
天津醫(yī)科大學(xué)優(yōu)秀博士畢業(yè)生
學(xué)術(shù)任職:
中國醫(yī)療保健國際交流促進(jìn)會泌尿健康分會委員
中華預(yù)防醫(yī)學(xué)會生育力保健分會委員
山西省醫(yī)師協(xié)會男科與性醫(yī)學(xué)分會委員
山西省社區(qū)衛(wèi)生健康專業(yè)委員會青年委員
中國科普作家協(xié)會醫(yī)學(xué)科普創(chuàng)作專業(yè)委員會委員
近五年承擔(dān)科研課題情況:
1. 國家自然科學(xué)基金青年科學(xué)基金項(xiàng)目,81800668,腺相關(guān)病毒對糖尿病膀胱基因治療的應(yīng)用及機(jī)制研究,2019/01-2021/12,22萬元。
2.國家自然科學(xué)基金面上科學(xué)基金項(xiàng)目,81970662,纖維細(xì)胞外泌體中內(nèi)質(zhì)網(wǎng)應(yīng)激相關(guān)凋亡miRNA介導(dǎo)糖尿病膀胱進(jìn)展的分子機(jī)制研究,2020/01-2023/ 12 ,55萬元。
3.國家自然科學(xué)基金青年科學(xué)基金項(xiàng)目,81302211,F(xiàn)KBP51調(diào)控去勢抵抗性前列腺癌形成的分子信號及機(jī)制研究,2014/01-2016/12,27萬元。
4.山西省應(yīng)用基礎(chǔ)研究項(xiàng)目面上青年基金項(xiàng)目,基于AAV9對糖尿病膀胱基因治療的應(yīng)用及機(jī)制研究,201801D221276,3萬。
5.山西醫(yī)科大學(xué)第一醫(yī)院博士科研基金,SERCA2a蛋白對糖尿病膀胱功能的修復(fù)及機(jī)制研究,YB161713,10萬。
代表性論著及近五年的代表性論文(限10項(xiàng)以內(nèi)):
1: Shang Z, Yu J, Sun L, Tian J, Zhu S, Zhang B, Dong Q, Jiang N, Flores-MoralesA, Chang C, Niu Y. LncRNA PCAT1 activates AKT and NF-κB signaling in castration-resistant prostate cancer by regulating the PHLPP/FKBP51/IKKα complex. Nucleic Acids Res. 2019 May 7;47(8):4211-4225. doi: 10.1093/nar/gkz108. PMID: 30773595; PMCID: PMC6486551.(SCI期刊,IF: 14.9)
2: Zhu S, Zhang Z, Zhang H, Liu Z, Liu M, Liu Q, Zang L, Wang L, Ji J, Wu B, Sun L, Zhang Z, Cao H, Wang Y, Wang H, Shang Z, Niu Y. DNA-repair status should be assessed in treatment-emergent neuroendocrine prostate cancer before platinum-based therapy. Prostate. 2022 Mar;82(4):464-474. doi: 10.1002/pros.24292. Epub2022 Jan 17. PMID: 35037281. (SCI期刊,IF: 2.8)
3: Ma X, Sun L. Construction and Validation of Protein Expression-related Prognostic Models in Clear Cell Renal Cell Carcinoma. J Cancer. 2023 Mar 27;14(5):793-808. doi: 10.7150/jca.81915. PMID: 37056387; PMCID: PMC10088890. (SCI期刊,IF: 3.9)
4: Shen P, Cao X, Sun L, Qian Y, Wu B, Wang X, Shi G, Wang D. KLF9 suppressescell growth and induces apoptosis via the AR pathway in androgen-dependent prostate cancer cells. Biochem Biophys Rep. 2021 Oct 12;28:101151. doi:10.1016/j.bbrep.2021.101151. PMID: 34703906
5: Yu J, Sun L, Hao T, Zhang B, Chen X, Li H, Zhang Z, Zhu S, Quan C, Niu Y,Shang Z. Restoration of FKBP51 protein promotes the progression of castration resistant prostate cancer. Ann Transl Med. 2019 Dec;7(23):729. doi:10.21037/atm.2019.11.127. PMID: 32042745; PMCID: PMC6990039.
6: Wu B, Lu X, Shen H, Yuan X, Wang X, Yin N, Sun L, Shen P, Hu C, Jiang H, WangD. Intratumoral heterogeneity and genetic characteristics of prostate cancer.Int J Cancer. 2020 Jun 15;146(12):3369-3378. doi: 10.1002/ijc.32961. Epub 2020 Mar 25. PMID: 32159858. (SCI期刊,IF: 6.4)
7: Ma Y, Sun L, Lin X, Zhang W, Wang D. Efficacy and safety of bipolar versus monopolar transurethral resection of bladder tumors: A meta-analysis of randomized controlled trials. J Cancer Res Ther. 2020;16(7):1588-1595. doi: 10.4103/jcrt.JCRT_539_20. PMID: 33565504. (SCI期刊,IF: 1.3)
8: Hu J, Tian J, Zhu S, Sun L, Yu J, Tian H, Dong Q, Luo Q, Jiang N, Niu Y,Shang Z. Sox5 contributes to prostate cancer metastasis and is a master regulator of TGF-β-induced epithelial mesenchymal transition through controlling Twist1 expression. Br J Cancer. 2018 Jan;118(1):88-97. doi:
10.1038/bjc.2017.372. Epub 2017 Nov 9. PMID: 29123266; PMCID: PMC5765224. (SCI期刊,IF: 8.9)
9: Shen P, Yin N, Sun L, Liu Y, Cao X. Diagnosis and treatment of bilateral adrenal pheochromocytoma with RET gene mutation combined with medullary sponge kidney: A case report. Medicine (Baltimore). 2023 Jun 9;102(23):e34022. doi: 10.1097/MD.0000000000034022. PMID: 37335636; PMCID: PMC10256389. (SCI期刊,IF: 1.6)