導(dǎo)師簡介
姓名:王宏勤 性別:男 政治面貌:中共黨員
學(xué)歷:研究生 學(xué)位:博士 職稱:教授
博、碩導(dǎo)師:博導(dǎo) 本崗位工作年數(shù):30年
研究方向:腦腫瘤、腦血管疾病基礎(chǔ)與臨床
榮譽稱號:山西省首批“三晉英才”-拔尖骨干人才,山西省首批學(xué)術(shù)技術(shù)帶頭人,第一完成人獲得山西省科技進(jìn)步獎二等獎1項,山西省高??萍歼M(jìn)步獎一等獎1項。
學(xué)術(shù)任職:山西醫(yī)科大學(xué)神經(jīng)外科碩導(dǎo)、博導(dǎo),國家衛(wèi)生健康委能力提升和繼續(xù)教育神經(jīng)外科專家委員會委員,山西省醫(yī)學(xué)會神經(jīng)外科專業(yè)委員會侯任主任委員,中國醫(yī)師協(xié)會神經(jīng)外科分會全國委員
近五年承擔(dān)科研課題情況:
國家自然基金面上項目-MicroRNA-195 在人腦膠質(zhì)瘤替莫唑胺化療耐藥中的作用及機(jī)制研究(81470115)
代表性論著及近五年的代表性論文(限10項以內(nèi))
Radiotherapy combined with anti-CEACAM1 immunotherapy to induce survival advantage in glioma.Discov Oncol. 2023 Mar 16;14(1):32.
MicroRNA-195 reverses the resistance to temozolomide through targeting cyclin E1 in glioma cells. Anticancer Drugs. 2019 Jan;30(1):81-88.
ANXA2 is a potential biomarker for cancer prognosis and immune infiltration: A systematic pan-cancer analysis.Front Genet. 2023 Jan 12;14:1108167.
Different changes in granulocyte-colony stimulating factor and its correlation with inflammatory biomarkers in patients after traumatic brain injury.Neuroreport. 2020 Mar 4;31(4):293-299.
Reduced expression of microRNA-497 is associated with greater angiogenesis and poor prognosis in human gliomas. Hum Pathol. 2016 Dec;58:47-53.
Abnormal expression of circulating and tumor-infiltrating carcinoembryonic antigen-related cell adhesion molecule 1 in patients with glioma.Oncol Lett. 2018 Mar;15(3):3496-3503.
Anti-miRNA-23a oligonucleotide suppresses glioma cells growth by targeting apoptotic protease activating factor-1.Curr Pharm Des. 2013;19(35):6382-9.
p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis.Mol Med Rep. 2015 Jun;11(6):4165-73.
Combined Blockade of T Cell Immunoglobulin and Mucin Domain 3 and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Results in Durable Therapeutic Efficacy in Mice with Intracranial Gliomas. Med Sci Monit. 2017 Jul 24;23:3593-3602.
The role of neuropeptide Y and aquaporin 4 in the pathogenesis of intestinal dysfunction caused by traumatic brain injury. J Surg Res. 2013 Oct;184(2):1006-12.